软骨滑从可浸透性的角度来看
Xuhao Yang1, Feng Gao1, Wenlong Song1
1State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China.
ACS nano
|April 2, 2025
概括
关节软骨滑依赖于其独特的可湿性,在超性和疏水性之间切换. 了解这种特性激发了人造软骨和低摩擦软执行器的设计.
科学领域:
- 生物材料科学 生物材料科学
- 部落学 (tribology) 是一个学科.
- 表面化学 表面化学
背景情况:
- 关节软骨在突液中表现出非常低的摩擦和磨损.
- 软骨可以在超性和疏水性状态之间动态切换可湿性.
- 这种独特的 Tribological 行为受到其组成和突液环境的影响.
研究的目的:
- 从湿度的角度来看,审查和讨论关节软骨滑.
- 探索软骨组成,脂层和可湿性之间的关系.
- 在各种刺激下提供对软骨滑机制的洞察.
主要方法:
- 审查关于软骨滑和可湿性现有的文献.
- 对脂层和突液超分子协同作用的分析.
- 讨论软骨的湿透性和滑性对剪切,pH,温度和电场等刺激的反应.
主要成果:
- 脂层显著影响软骨的湿透性.
- 突液的高分子协同作用增强了软骨的滑.
- 软骨的可湿性和滑性是由外部刺激调节的.
结论:
- 湿度是理解关节软骨滑的关键因素.
- 软骨湿度的洞察力可以指导人工软骨和软执行器的设计.
- 需要进一步的研究来应对软骨滑和生物仿真应用的可湿性方面的挑战.
相关概念视频
Structural Joints: Synovial Joints
3.2K
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
3.2K
Growth of Cartilage and Bone Tissue
3.0K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.0K
Glycosaminoglycans
4.6K
Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
4.6K
Structural Joints: Cartilaginous Joints
2.0K
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
2.0K
Structural Classification of Joints
3.1K
Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
A fibrous joint is where the adjacent bones are united by fibrous connective...
A fibrous joint is where the adjacent bones are united by fibrous connective...
3.1K
Joints
32.5K
Joints, also called articulations or articular surfaces, are points at which ligaments or other tissues connect adjacent bones. Joints permit movement and stability, and can be classified based on their structure or function.
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
32.5K


