过敏性鼻炎:从童年到青春期的发病率和缓解-一项前性研究
Styliana Vasileiadou1, Emma Goksör1, Göran Wennergren1
1Department of Paediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
概括
过敏性鼻炎 (AR) 发病率在8-19岁之间很高,特别是在女孩身上. 敏感性增加了AR风险和降低了缓解率,男孩的缓解率更高.
科学领域:
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 有限的纵向数据存在过敏性鼻炎 (AR) 发病率和从童年到成年期的缓解.
- 这项研究解决了在这个关键生命阶段对AR发展和解决问题的综合数据的需求.
研究的目的:
- 估计8岁至19岁年龄组中过敏性鼻炎 (AR) 的发病率和缓解率.
- 确定与AR发展和缓解相关的关键风险因素.
主要方法:
- 一项纵向研究涉及2250名参与者,他们年龄分别为8岁和19岁.
- 对于1338名参与者的子组,在两种年龄段进行了空气传播过敏原的皮肤刺伤测试 (SPT).
- 在瑞典北部的三个市镇采用问卷和SPT收集数据.
主要成果:
- 从8岁到19岁的AR累积发病率为33.6%,女孩的发病率比男孩 (29.8%) 高 (37.4%).
- 8岁 (aOR 3.75) 或8-19岁 (aOR 2.57) 和女性性别 (aOR 1.71) 之间的敏感性是发展AR的重要危险因素.
- 整体缓解率为40.0%,男孩的缓解率 (45.4%) 比女孩 (32.2%) 高得多. 敏感性降低了缓解的可能性.
结论:
- 过敏性鼻炎 (AR) 在儿童和青少年时期发生率很高,性别差异明显.
- 敏感化是一个关键因素,影响了AR的发病和解决.
- 研究结果强调了早期敏感性检测对于管理AR进展和缓解的重要性.
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