囊性纤维化护理的全球化
1Center for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Palo Alto, California, USA.
Current opinion in pediatrics
|April 2, 2025
概括
囊性纤维化 (CF) 护理在全球范围内取得了进展,新疗法在低收入和中等收入国家 (LMICs) 提高了知识. 然而,获得关键的CFTR调节剂药物仍然是公平护理的重大障碍.
科学领域:
- 医学科学 医学科学 医学科学
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 囊性纤维化跨膜导电性调节器 (CFTR) 基因的克隆彻底改变了囊性纤维化 (CF) 研究和治疗.
- 显著的科学进步已经导致有效的疗法针对CF的基本缺陷.
- 低收入和中等收入国家 (LMICs) 的护理人员和患者越来越多地了解CF管理.
研究的目的:
- 审查囊性纤维化 (CF) 的全球状况,特别是在LMICs.
- 突出CF的普遍发生和区域发病率变化.
- 审查旨在传播最佳护理实践和减少护理差异的国际合作努力.
主要方法:
- 审查关于囊性纤维化目前的科学文献.
- 全球CF发病率和流行率数据的分析.
- 评估改善CF护理的国际倡议.
主要成果:
- 囊性纤维化 (CF) 发生在世界各地,发病率因地理区域而异.
- 国际合作正在积极合作,分享CF护理的最佳实践.
- 目前正在努力弥合高收入和LMIC之间的CF护理差距.
结论:
- 尽管取得了进展,但在囊性纤维化 (CF) 护理方面,富裕国家和LMIC之间仍然存在显著的差异.
- 改善CF护理的国际努力受到先进治疗方法有限的限制的挑战.
- 限制使用CFTR调节剂药物是全球实现公平CF护理的主要障碍.
相关概念视频
Cystic Fibrosis: Management
117
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
117
Cystic Fibrosis: Pathogenesis
157
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
157
Issues And Trends In Healthcare Delivery System
5.5K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.5K
Methods Of Healthcare Delivery System
3.1K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
3.1K
Primary Healthcare Services
1.3K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.3K
Nursing Clinical Information System
724
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
724


