用氨酸激酶抑制剂治疗的癌症患者报告的结果措施:一项方法研究研究
Ana Maria Teixeira Pires1, Julie Ann Ponto2, Eliana Cavalari Teraoka1
1Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.
Revista brasileira de enfermagem
|April 2, 2025
概括
这项研究验证了PRO-CTCAE® Estudo PROM-TKI Brasil仪器,用于治疗氨酸激酶抑制剂 (TKI) 的癌症患者. 该仪器证明了内容的有效性和适合患者使用.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 方法论 方法论 方法论
背景情况:
- 氨酸激酶抑制剂 (TKI) 治疗对于癌症治疗至关重要.
- 经过验证的结果测量仪器对于监测TKI治疗期间的患者体验至关重要.
- 现有的工具可能需要针对特定患者群体和治疗方法进行调整.
研究的目的:
- 为了验证对接受TKI治疗的癌症患者的结果测量仪器的内容.
- 评估验证仪器对目标患者群体的可理解性和适用性.
- 建立PRO-CTCAE®研究PROM-TKI巴西作为一个可靠的工具TKI治疗.
主要方法:
- 通过综合性审查进行仪器开发的方法研究.
- 使用Delphi技术与专家法官确定内容的有效性.
- 进行试点测试,以评估癌症患者的可理解性和适用性.
主要成果:
- 在PRO-CTCAE® Estudo PROM-TKI Brasil的构造中,最初使用了16个项目,在Delphi技术回合后改进到20个项目.
- 专家验证的内容有效性指数 (CVI) 为0.878.8.
- 试点测试的CVI为1.0,表明在患者中具有很高的可理解性和适合性.
结论:
- PRO-CTCAE® Estudo PROM-TKI Brasil仪器已经证明了在接受TKI治疗的患者中使用的有效性.
- 该仪器既易于理解,又适合接受TKI治疗的癌症患者.
- 这种经过验证的仪器可以帮助在TKI治疗期间监测患者报告的结果.
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