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Updated: May 17, 2025

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基于生物信息学分析的DM2和牙周炎的潜在诊断标志物和治疗目标

Rong Luo1, Zhenye Liang1, Huijun Chen1

  • 1Department of Pharmacy, Taizhou First People's Hospital, Taizhou, China.

PloS one
|April 2, 2025
PubMed
概括

这项研究确定了S100A9作为关键基因,将2型糖尿病和牙周炎联系起来. 通过TLR4信号通路,S100A9可能促进疾病的进展,提供潜在的诊断和治疗点.

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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