放射性评分,喘和NSAID加重的呼吸道疾病预测了慢性鼻炎的复发
Markus Lilja1,2,3, Anni Koskinen1,2, Sari Hammarèn-Malmi1
1Department of Allergology, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Clinical and translational allergy
|April 2, 2025
概括
来自CT扫描的鼻腔放射学 (SR) 和隆德-麦凯 (LM) 评分预测慢性鼻炎 (CRS) 复发. 高分数和喘等疾病表明需要修复手术或进一步治疗的风险更高.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 慢性鼻炎 (CRS) 是一种普遍的疾病,需要有效的管理策略.
- 评估术后复发的风险对于患者的治疗结果和医疗保健资源分配至关重要.
研究的目的:
- 评估从鼻计算机断层扫描 (CT) 扫描中得出的鼻放射学 (SR) 和隆德-麦凯 (LM) 评分的预测值,以预测CRS患者的术后复发.
- 确定可协助临床决策的成像生物标志物,用于CRS管理.
主要方法:
- 一组483名CRS患者 (年龄为12-80岁) 接受了常规的鼻CT扫描.
- SR 评分是基于正面隙阻塞和轮机可视化 (0-6 分) 开发的.
- 统计分析包括非参数,生存和Cox的比例危险模型来评估关联.
主要成果:
- 高的手术前SR或LM得分显著预测了需要修订内镜外科手术 (ESS) 和口服皮质类固醇疗程的需要.
- 在多变量分析中,SR得分和喘或NSAID加重呼吸道疾病 (N-ERD) 的病史都与修订ESS的风险增加显著相关.
- 在CT扫描后平均3.2年内,在28.0%的患者中进行了ESS修订.
结论:
- 隆德-麦凯 (LM) 和鼻腔放射 (SR) 评分是慢性鼻炎 (CRS) 复发的有价值预测指标.
- 喘或NSAID加剧呼吸道疾病 (N-ERD) 的病史进一步提高了CRS复发的预测.
- 这些成像和临床因素可以帮助临床医生做出有关CRS治疗和随访的明智决策.
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