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Updated: May 16, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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通过Tet1/3的发育表观遗传编程决定了外围CD8T细胞的命运

Kara M Misel-Wuchter1,2,3, Andrew L Thurman3, Jordan T Johnson4

  • 1Inflammation Program, University of Iowa, Iowa City, IA, USA.

EMBO reports
|April 2, 2025
PubMed
概括

在T细胞发育过程中,Tet酶 (Tet1/3) 对于产生长寿CD8记忆T细胞至关重要. 切除Tet1/3导致分化为短寿命的效应细胞,突出显示它们在免疫记忆中的重要作用.

关键词:
脱甲基化 DNA 脱甲基化效应器 CD8 T 细胞表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.记忆 CD8 T 细胞在T细胞发育过程中

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