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Updated: Jun 15, 2026

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在巨细胞感染期间分析沙门氏菌转录动态,使用全面的报告员库

Taylor H Nguyen1, Benjamin X Wang2, Oscar R Diaz2

  • 1Department of Bioengineering, Stanford University, Stanford, CA, USA.

Nature microbiology
|April 2, 2025
PubMed
概括

沙门氏菌Typhimurium通过改变基因表达来适应宿主环境. 这项研究揭示了新的转录动力学和代谢转变,包括稳态,这对于巨细胞内的细菌生存至关重要.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...