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Updated: May 17, 2025

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通过阿托瓦昆诱导的PERK/eIF2α信号轴的激活会减轻代谢性辐射敏感化

Jie Feng1, Varun Pathak2, Niall M Byrne1

  • 1School of Pharmacy, Queen's University Belfast, BT9 7BL, Belfast, Northern Ireland, UK.

Cell communication and signaling : CCS
|April 2, 2025
PubMed
概括

阿托瓦昆破坏了瘤细胞的呼吸,最初使癌细胞对辐射敏感. 然而,它会触发一种适应性应激反应,从而产生抗性,从而限制其有效性. 抑制这种应激反应可以恢复atovaquone的功能.

关键词:
自自是一种自的过程.压力ERER压力ERER压力氧气过低是因为缺氧.辐射敏感化 辐射敏感化

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