相关实验视频

Updated: May 16, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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赛亚姆:半参数适应信息辅助的多目标进化对蛋白质-连接体对接的进化.

Wei Xiao1, Haichuan Shu1, Chen Xu1

  • 1School of Electronic and Information, Shanghai Dianji University, Shanghai, China.

Chemical biology & drug design
|April 3, 2025
PubMed
概括

一种新的计算方法,SAIAME,通过优化 conformational 采样来改善蛋白质 - 连接体对接. 这种方法提高了预测药物分子结合姿势和相亲关系的准确性,用于基于结构的药物发现.

关键词:
渐变增强增强渐变的增强多目标进化的多目标进化.人口规模减少 人口规模减少蛋白质-合物对接半参数调整的调整方法

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