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直接导致内感染的巴拉穆提亚氨菌脑炎:一个病例报告

Yuhan Liang¹, Yanhong Liu¹, Zelong Chen¹

¹Department of Radiology, The First Medical Center, Chinese PLA General Hospital, Beijing China.

Radiology case reports

|April 3, 2025

概括

巴拉穆提亚氨菌脑炎 (BAE) 是一种罕见的,致命的中枢神经系统感染. 早期诊断是很困难的,因为像脑炎这样的症状出现在皮肤病变之前,这凸显了迅速识别Balamuthia mandrillaris的必要性.

科学领域:

神经学神经学
传染性疾病传染性疾病
病理学病理学病理学

背景情况:

巴拉穆提亚虫脑炎 (BAE) 是一种罕见的,致命的中枢神经系统感染,由自由生活的虫巴拉穆提亚虫 (Balamuthia mandrillaris) 引起.
巴拉穆提亚直接入侵大脑使得早期诊断具有挑战性,因为明显的早期预警信号和先前的全身或皮肤症状往往不存在.
阿米巴可以通过各种途径进入人体,包括呼吸道,皮肤或胃肠道,导致侵袭性脑炎.

研究的目的:

在35岁的男性中报告一种致命的Balamuthia氨基脑炎 (BAE) 病例.
强调BAE的诊断挑战和高死亡率,特别是当神经症状是最初的表现时.
强调在有相关暴露史的不明原因脑炎病例中考虑Balamuthia mandrillaris的重要性.

主要方法:

一个35岁的男性患者的病例报告,患有Balamuthia氨菌脑炎.
诊断主要基于病理发现.
对患者病史的审查,包括接触地下矿山和生牛肉消费.

主要成果:

患者表现出神经症状,没有先前的全身或皮肤表现.
感染被认为是通过呼吸道或胃肠道进入的.
延迟诊断和缺乏有效治疗导致患者在症状出现后大约2个月死亡.

结论:

BAE是一种罕见的,经常致命的感染,死亡率很高.
神经症状作为第一个迹象,没有先前的系统或皮肤问题,复杂早期Balamuthia mandrillaris诊断.
对于患有无法解释的脑炎和脑的患者,特别是那些潜在的环境暴露患者,考虑Balamuthia mandrillaris至关重要.

关键词:

这种植物是Balamuthia mandrillaris.脑炎是一种脑炎.颗粒状菌脑炎的发生.

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