静脉洛卡因在胃肠内镜中的应用:一项随机对照试验
Peng Zhang1, Jin Zhang1, Ying Zhao1
1Department of Anesthesiology, the Second People's Hospital of Wuhu, Wuhu, Anhui, 241000, People's Republic of China.
Local and regional anesthesia
|April 3, 2025
概括
хлоропрокаин显著降低了在胃肠内镜检查期间的普罗波福使用和注射疼痛. 这种麻醉方法也改善了患者的康复时间,并减少了术后的疼痛.
科学领域:
- 麻醉学 麻醉学
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 普罗波是胃肠内镜的常见镇静剂,但会导致低血压和注射疼痛等不良影响.
- 这项研究研究了洛卡因作为一个潜在的补充剂,以减轻这些与普罗波相关的问题.
研究的目的:
- 为了评估罗可因是否可以降低胃肠内镜期间的propofol消耗.
- 评估罗普罗卡因在减少普罗波福尔注射疼痛和改善患者康复方面的有效性.
主要方法:
- 60名患者被随机分为两组:一组接受甲 (CP组) 和一组接受盐水的对照组 (C组).
- 两组都接受了sufentanil和propofol的镇静作用;CP组接受了额外的罗普罗卡因输液.
- 群体之间比较了醇消费,不良事件,注射疼痛和恢复指标.
主要成果:
- 组CP需要显著少的普罗波 (119±14毫克) 比组C (148±18毫克).
- 在CP组中,注射疼痛的发生率较低 (P=0.007).
- 组CP显示恢复时间缩短,PACU停留,以及术后疼痛得分.
结论:
- 静脉注射的 хлоропрокаин有效地降低了胃肠内镜中对普罗波的需求.
- хлоропрокаин可以缓解与普罗波福相关的注射疼痛,并促进患者的康复.
- 这表明 хлоропрокаин是胃肠道手术期间镇静的有益辅助剂.
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