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案例报告:纹身肉类瘤与上皮细胞粒瘤阳性Propionibacterium

Yuiko Masuda¹, Hiroko Okabayashi¹, Kimitaka Akaike¹

¹Department of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.

Frontiers in medicine

|April 3, 2025

概括

纹身肉类发病症,纹身部位的颗粒状反应,在一个患有全身症状的患者中被诊断出. 这项研究表明,Propionibacterium acnes可能在其发展中发挥作用.

科学领域:

皮肤病学皮肤病学
免疫学免疫学免疫学
微生物学微生物学

背景情况:

纹身类型硬化症呈现为局限于纹身部位的颗粒状反应,通常伴有全身类型硬化症症状.
纹身沙尔科病的确切原因是未知的,纹身颜料被怀疑是免疫反应的触发因素.

研究的目的:

报告一个纹身类瘤发病的病例.
调查Propionibacterium acnes在纹身沙丘病的病因学中的潜在作用.

主要方法:

一名28岁的男性患者的临床表现,纹身部位出现皮下结节和全身症状.
诊断工作包括成像 (淋巴腺病,肺微粒),实验室测试 (ACE,sIL-2R,,功能) 和皮肤活检.
皮肤活检的组织病理学检查与特殊染色,包括对Propionibacterium acnes的抗体染色.

主要成果:

患者表现出皮下结节,双侧状和中状淋巴腺病变,肺微结节,高ACE和sIL-2R,高血,以及功能障碍.
皮肤活检显示了上皮细胞颗粒瘤.
在颗粒瘤内对Propionibacterium acnes的抗体染色呈阳性;其他染色是负的. 病变和全身症状自发地消失.

结论:

在颗粒瘤中发现Propionibacterium acnes的存在表明,这种细菌在纹身沙丘症的发病过程中可能发挥作用.
在没有治疗的情况下,皮肤和全身表现的自发解决发生了,这表明这种情况的自我限制过程.

关键词:

这种细菌是Cutibacterium acnes.这种细菌是Propionibacterium acnes.这种类型的麻症是有毒的.纹身纹身纹身纹身纹身 Sarcoidosis 这种疾病.

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