在男性的尿路炎中,Mycoplasma penetrans. 一个病例控制研究研究
Luis Piñeiro1, Pedro Idigoras1, Ayla Manzanal1
1Department of Microbiology, Donostia University Hospital, Biogipuzkoa Health Research Institute, OSI Donostialdea, University of the Basque Country (UPV/EHU), San Sebastián, Spain.
Frontiers in microbiology
|April 3, 2025
概括
质体透菌与男性无法解释的尿路炎有关,特别是在与男性发生性关系的男性中. 检测这种新出现的病原体可以改善诊断非淋巴球菌性尿路炎病例.
科学领域:
- 微生物学 微生物学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
背景情况:
- 许多尿路炎病例缺乏明确的微生物学诊断.
- 菌质透菌是一种新兴的病原体,涉及尿路炎,特别是在与男性发生性关系的男性 (MSM) 和艾滋病毒感染者中.
研究的目的:
- 为了研究Mycoplasma penetrans和男性异常性尿路炎之间的关联.
- 评估在不明原因的尿路炎病例中检测M. penetrans的诊断效用.
主要方法:
- 来自男性的尿道样本使用内部实时PCR进行了M. penetrans的分析.
- 55例异常性尿路炎病例与对照组之间的比较 (102例确诊尿路炎,91例健康对照).
- 标准技术 (克染色,培养,PCR,血清学) 用于其他性传播感染.
主要成果:
- 在12.7%的异形性尿路炎病例中检测到M. penetrans DNA.
- 在任何对照组中都没有发现M. penetrans (p < 0.001).
- M. penetrans阳性个体没有感染艾滋病毒;六人是MSM.
结论:
- 结果表明,在男性中,M. penetrans感染和尿路炎之间存在显著的关联.
- 检测M. penetrans可能有助于诊断异常性尿路炎的病例.
- 这一发现可能会改善非冠状病毒球菌性尿路炎的诊断产量.
关键词:
菌质透透体 菌质透体 透体 菌质透体新兴病原体新兴的病原体异形性尿路炎 异形性尿路炎男人男人的男人的男人的男人性传播感染性传播感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性感染性
相关概念视频
01:26Sexually Transmitted Infections
2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
2.0K
01:20Disorders of the Male Reproductive System
5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
01:27Acute Pyelonephritis I: Introduction
1.5K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.5K
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
859
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
859
01:28Microbiota of the Urogenital Tract
59
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
59
01:14Atypical Pneumonia
88
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
88