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Updated: May 16, 2025

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对早期复发性乳腺癌的基因组洞察:预后挑战和突变景观

Yixuan Wang1, Lianru Zhang2, Yanan Du2

  • 1Department of Oncology, Nanjing Drum Tower Hospital, Drum Tower Clinical Medical College, Jiangsu University, Nanjing, 210009, People's Republic of China.

OncoTargets and therapy
|April 3, 2025
PubMed
概括

早期复发的乳腺癌患者面临着不良预后和有限的治疗选择. 基因分析揭示了TP53等关键突变,为个性化治疗提供了新的途径.

关键词:
乳腺癌 乳腺癌 乳腺癌临床病理学特征临床病理学特征早期复发的早期复发基因测序是基因测序的方法之一.预后特征 预后特征 预后特征

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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