相关实验视频
Updated: May 16, 2025

09:25
A Protocol to Acquire the Degenerative Tenocyte from Humans
Published on: June 9, 2018
7.3K
身体不成熟的患者的半肌具有较低的I型原蛋白含量
Yushin Mizuno1,2, Yasushi Takata1, Kazuaki Yoshioka3
1Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan.
概括
不成熟的半肌肌比成熟的肌和四头肌肌更少的I型原蛋白. 原组成的这种差异凸显了肌结构的发育变化.
科学领域:
- 生物化学 生物化学
- 整形外科手术 整形外科手术
- 运动医学 运动医学
背景情况:
- 肌的组成,特别是原类型,影响机械性质.
- 了解肌原蛋白的发育变化对于伤害预防和康复至关重要.
研究的目的:
- 为了研究半肌和四头肌肌的原成分 (I型和III型).
- 为了在这些肌中比较不同水平的物理成熟度中的原蛋白含量.
主要方法:
- 分析了接受带重建的70名患者的组织样本.
- 免疫组织化学和共聚焦显微镜量化了I型和III型原蛋白的百分比.
- 患者根据年龄和体通透度被分为不成熟,年轻和成年人群.
主要成果:
- 与年轻人 (98.9%) 和成年人 (97.0%) 组相比,未成熟的半状肌显示出明显较低的I型原蛋白 (54.2%).
- 在未成熟的个体中,半肌的I型原蛋白比四头肌 (98.4%) 低.
- 四肌原蛋白组成在所有成熟年龄组中仍然相对较高.
结论:
- 未成熟患者的半肌表现出明显的原蛋白形状,I型原蛋白减少.
- 这些发现表明,半肌和四肌肌之间原合成和组织的发育差异.
- 了解这些成熟变化对于体育医学和骨科的临床应用至关重要.
相关概念视频
Elastin is Responsible for Tissue Elasticity
2.3K
Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
2.3K
Fibril-associated Collagen
2.5K
Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
2.5K
Dense Connective Tissue
7.2K
Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
Dense Regular Connective Tissue
In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...
Dense Regular Connective Tissue
In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...
7.2K
Phases of Wound Repair
5.7K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
5.7K
Embryonic Connective Tissues
4.1K
During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development.
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development.
4.1K
Type IV Collagen of Basal Lamina
2.1K
Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
A type IV collagen molecule has six alpha chains which can...
A type IV collagen molecule has six alpha chains which can...
2.1K

