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在儿科玻璃眼瘤中Preserflo MicroShunt的有效性和安全性

Susana Rebocho Duarte^1,2, Afonso Lima-Cabrita^1,2, Rafael Correia Barão^1,2

¹Department of Ophthalmology, Unidade Local de Saúde de Santa Maria, Lisboa, Portugal.

Journal of glaucoma

|April 3, 2025

概括

在两年时间内,Preserflo植入物有效降低了眼内压力,并减少了儿科患者对青光眼的药物治疗需求. 这项研究发现,这种青光眼治疗选择具有有利的安全性.

科学领域:

眼科医生眼科眼科
手术创新在外科创新.
儿科玻璃眼治疗的管理方法

背景情况:

儿科玻璃眼症带来独特的管理挑战.
普雷斯弗洛设备为眼内压力 (IOP) 控制提供了一种新的外科手术方法.
对年轻患者的疗效和安全性进行评估至关重要.

研究的目的:

评估Preserflo设备在选定的儿科绿眼病病例中的有效性和安全性.
为了确定对眼内压力和药物需求的影响.
在两年时间内评估长期结果.

主要方法:

追溯的多中心观察性研究.
包括使用Preserflo植入的儿科患者 (≤18岁) 和≥6个月的随访.
主要结局:通过IOP范围 (6-21mmHg) 定义的手术成功,降低≥20%或≥30%,没有进一步的手术,没有严重的并发症. 二次结局包括IOP,药物使用和不良事件.

主要成果:

平均IOP从基线时的27.8 mmHg显著降低到12个月后的14.2 mmHg和24个月后的14.6 mmHg (P <0.001).
在24个月内,绿眼瘤的平均用药量从2.9降至0.9 (P=0.006).
合格的手术成功率为60% (标准A) 和50% (标准B) 在12个月,和45%在24个月. 没有观察到危及视力的并发症.

结论:

普雷塞弗洛植入证明了显著的IOP降低和降低了小儿玻璃眼患者的药物需求.
该设备在2年的随访期间表现出良好的安全性,没有危及视力的并发症.
现实数据表明,Preserflo是为儿童青光眼癌的特定病例提供安全有效的手术选择.

关键词:

孩子们的孩子们的孩子们的孩子们.过手术是一项过手术.玻璃眼 glaucoma 玻璃眼玻璃眼玻璃眼玻璃眼青光眼的排水植入物青光眼排水植入物

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