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Updated: May 17, 2025

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Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
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在德国普通人口中,低副甲状腺症患者问卷 (HPQ28) 的规范值
Christian Trummer1,2, Martina Blaschke1,3, Deborah Quint1
1Clinic of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.
Journal of patient-reported outcomes
|April 3, 2025
概括
这项研究在德国人群中确定了28项 (HPQ28) 的低甲状腺症患者问卷的规范值. 研究结果显示,年龄和性别显著影响报告的症状,女性和老年人遇到更多的投诉.
科学领域:
- 内分泌学和患者报告的结果.
背景情况:
- 低甲状腺症 (HypoPT) 显著影响患者的生活质量 (QoL),尽管控制生物化学标志物.
- 低甲状腺功能障碍患者问卷有28项 (HPQ28) 已被开发用于量化HypoPT症状.
研究的目的:
- 在德国一般人口中确定HPQ28的规范值.
- 为评估HypoPT患者的症状负担建立一个基准.
主要方法:
- 来自德国普通人口的代表性样本2506个人完成了HPQ28.
- 收集的数据包括5个HPQ28尺度 (疼痛和,神经素质症状,生命力丧失,抑郁和焦虑,胃肠道症状) 的社会人口统计信息和反应,以及三个单个项目 (麻木/,记忆,心跳).
主要成果:
- 在所有HPQ28尺度和项目中,女性报告的投诉明显高于男性 (p < 0.01).
- 年龄显著影响了所有尺度和项目,除了胃肠道症状 (p < 0.001).
- 回归分析证实了大多数HPQ28分数中年龄和性别的线性趋势.
结论:
- 这项研究为德国普通人口中HPQ28提供了第一个规范性数据.
- 年龄和性别是影响普通人群症状感知和负担的关键因素.
- 这些规范值对于准确解释HypoPT患者的HPQ28结果至关重要.
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