在加利福尼亚州的西班牙裔集团中,儿童癌症风险很大
Darcy Van Deventer1, Zuelma A Contreras1, Shiwen Li1
1Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, USA.
Journal of immigrant and minority health
|April 3, 2025
概括
在怀孕期间居住在西班牙裔飞地之外可能会增加西班牙裔儿童患儿癌症的风险. 然而,这种关联因癌症类型,母亲的出生和位置而异,这表明环境对儿科癌症的影响复杂.
科学领域:
- 环境流行病学环境流行病学
- 儿科瘤学 儿科瘤学
- 健康的社会文化决定因素
背景情况:
- 同文化化,通常是通过居住在西班牙裔飞地中进行的,与不良的怀孕和儿童健康结果有关.
- 了解社区特征对儿童癌症风险的影响对于公共卫生干预至关重要.
研究的目的:
- 调查怀孕期间母亲在西班牙裔飞地居住与西班牙裔儿童患儿癌症风险之间的关联.
- 根据母亲的出生和地理位置来探索这种关联的变化.
主要方法:
- 从加利福尼亚州的出生记录 (1988-2013) 中利用了6111例癌症病例和12443例对照的病例控制研究设计.
- 使用美国十年人口普查和美国社区调查 (ACS) 数据,根据人口普查区域创建了西班牙裔飞地索引.
- 采用多变量逻辑回归来估计围居住对儿童癌症风险的影响,按母亲的出生分层.
主要成果:
- 母亲在较少的封闭区居住与拉布多米索尔科马风险增加有关 (OR=1.62).
- 对于外国出生的母亲来说,居住在不太像飞地这样的地区与视网膜母细胞瘤风险降低有关 (OR=0.59).
- 在洛杉矶县,居住在不太像封闭区的社区与更高的拉布多米索尔科马 (OR=2.71) 和威尔姆斯瘤 (OR=2.23) 的几率相关.
结论:
- 居住在西班牙裔飞地并没有统一地降低儿童癌症风险;生活在飞地之外与特定癌症的几率较低有关.
- 根据母亲的出生和居住县,观察到癌症风险的显著差异,突出了复杂的环境和社会文化相互作用.
- 这些发现强调了需要细微的方法来理解邻里对儿科癌症差异的影响.
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