患者报告的生活质量结果测量术后的口腔切除术
Linda X Yin1, Christine M Lohse2, Kathleen J Yost2
1Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, Rochester, Minnesota.
JAMA otolaryngology-- head & neck surgery
|April 3, 2025
概括
开发和验证了一种新的患者报告的生活质量 (QOL) 指数,用于切除术恢复. 胸腔切除术生命质量指数显示了在评估手术后患者结果的卓越可靠性和有效性.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 患者报告的结果
背景情况:
- 口腔切除术的恢复缺乏经过验证的患者报告的生活质量 (QOL) 仪器.
- 现有的工具不能完全捕捉患者为中心的结果的多维方面.
研究的目的:
- 建立和验证一个全面的英语患者报告的QOL仪器,专门用于胸膜切除术恢复.
- 为了开发口腔切除术生命质量指数 (PQOLI).
主要方法:
- 进行了两阶段的调查研究,包括一个单一机构的队列和一个匿名的基于网络的调查.
- 探索性因子分析,克朗巴赫α和类内相关系数被用于评估有效性和可靠性.
- 最终的工具被改进为33个项目,跨越6个领域和2个独立项目.
主要成果:
- 最终的口腔切除术生命质量指数包括6个领域的33个项目,显示出出色的内部有效性 (Cronbach α ≥ 0.77).
- 该仪器显示了非常好的测试-重复测试可靠性 (类内相关系数为0.82-0.93).
- 较低的QOL分数与年轻的年龄和恶性瘤有关.
结论:
- 切除术生命质量指数是一种经过验证的仪器,具有出色的内部有效性和测试-重试可靠性.
- 这种工具可以帮助改善临床实践的质量,并作为未来胸膜切除试验的关键结果指标.
- 建议进行进一步的外部验证.
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