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Updated: May 16, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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通过分子内多米诺 / 螺旋循环化构建1,6-无水体功能化碳水化合物融合的螺旋染色素

Nicole Jankowski1, Christopher Hager1, Holly Arcure2

  • 1Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, United States.

Carbohydrate research
|April 3, 2025
PubMed
概括

一个新的合成路径使用多米诺反应创建了新的碳水化合物融合的螺旋-染色. 这些有效合成的化合物在初步测试中显示出令人失望的抗真菌特性.

关键词:
这是一种Dihydrolevoglucosenone.内部分子多米诺反应螺旋-染色体是一种螺旋循环化 螺旋循环化

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