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Updated: May 16, 2025

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在肺腺癌中具有侵略性病理特征的基因组分析

Yi-Duo Lin1, Hong-Ji Li1, Hui-Zhao Hong2

  • 1School of Medicine, South China University of Technology, Guangzhou, China; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Lung cancer (Amsterdam, Netherlands)
|April 3, 2025
PubMed
概括

淋巴血管入侵 (LVI) 和通过空气空间传播 (STAS) 等病理特征与肺腺癌中的特定基因突变相关. 这些发现为瘤分类和预测患者存活率提供了新的见解.

关键词:
基因组特征分析 基因组特征分析来自IASLC分级系统的3级模式肺部腺癌是肺部腺癌.淋巴血管的入侵 淋巴血管的入侵通过空气空间传播.

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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