对早期发病的胎儿贫血的考虑和方法,由于红细胞合免疫接种
1Department of Women's Health Dell Medical School - UT Health Austin and the Comprehensive Fetal Center Dell Children's Medical Center, Austin, TX, USA.
概括
胎儿和新生儿早期血溶性疾病 (EOS-HDFN) 被定义为22周之前的胎儿死亡或水. 管理包括早期DNA分析,多普勒超声波和潜在的免疫调节或子宫内输血.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿科学 新生儿科学
- 遗传学 遗传学 是一个
背景情况:
- 胎儿和新生儿早期出血性疾病 (EOS-HDFN) 缺乏标准化的定义.
- 在怀孕20-22周之前的先前子宫内输血 (IUT) 系列报告了20%的围产期死亡率.
研究的目的:
- 为EOS-HDFN提出一个定义.
- 概述一个管理策略,以后的怀孕与历史的EOS-HDFN.
主要方法:
- 在怀孕10-12周时免费进行胎儿DNA分析.
- 每周的中脑动脉峰值缩速度 (MCA-PSV) 多普勒超声波从15周的怀孕.
- 考虑从怀孕10-12周开始进行免疫调节 (IVIG,血酶).
主要成果:
- 拟议的定义:胎儿死亡,胎儿水,或在妊娠20-22周之前需要IUT.
- 在20周之前,可以使用腹腔内输液装置,稍后转向血管内输液装置.
- 新生儿Fc受体阻塞是潜在的未来治疗方法.
结论:
- 对于EOS-HDFN来说,一个明确的定义和早期的,积极的管理是至关重要的.
- 非侵入性和最小侵入性监测和治疗策略是关键.
- 新兴的疗法可能会减少对侵入性手术的需要.
关键词:
在EOS-HDFNN中使用.FcRNN 在线阅读胎儿和新生儿的血液溶解性疾病IUTUT 这是一个很好的方法.IVIGIG IVIGIG 这是一个很好的例子.在子宫内输血输血.静脉注射的免疫球蛋白是一种免疫球蛋白.在LITIT中,我们可以看到LIT.淋巴细胞输液疗法是淋巴细胞输液疗法.新生儿Fc受体 新生儿Fc受体血转化 (Plasmapheresis) 是一个过程.这是一个TPE.更多相关视频
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