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Updated: May 16, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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一系列新型三环性STING激活剂的合成和结构-活性评估

Sourav Basu1, Sandip Middya1, Ritesh Shrivastava1

  • 1Curadev Pharma Pvt. Ltd., B-87, Sector 83, Noida, 201305, Uttar Pradesh, India.

European journal of medicinal chemistry
|April 3, 2025
PubMed
概括

研究人员开发了具有强大人类刺痛活性的新型小分子刺痛激活剂. 化合物68选择性地激活了人类的STING,激活了免疫路径,并抑制了小鼠的瘤生长.

关键词:
细胞因子 (cytokines) 是一种细胞因子.免疫治疗是一种免疫疗法.干扰素基因 干扰素基因刺痛是一种刺痛.

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