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Updated: May 16, 2025

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
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Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

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药物从多塞塔塞尔捕获的核心交叉链接的聚合物细胞中释放:基于临床数据的种群药理学建模方法

Pascale C S Rietveld1, Stijn L W Koolen2, Stefan Zeiser3

  • 1Department of Clinical Pharmacy, Erasmus MC, Rotterdam, the Netherlands; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands; Rotterdam Clinical Pharmacometrics Group, the Netherlands.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|April 3, 2025
PubMed
概括

这项研究模拟了从CPC634纳米颗粒中释放多塞 (DTX) 的模型,发现pH显著影响药物释放率. 优化纳米颗粒设计以依赖pH的释放对于有效的癌症治疗至关重要.

关键词:
CPC63434 公司简介癌症 癌症 癌症 癌症化疗 化疗是一种化学疗法.有控制的药物释放.核心交叉连接的聚合物微粒.多塞塔克塞尔 (Docetaxel) 是一种人口的药理动力学.

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