在2002年至2024年期间,对风湿性关节炎的GWAS进行了图书统计分析
Wen-Hui Wang1,2,3, Ming-Hui Xia4,5,6, Xin-Ru Liu4,5,6
1Center for Genetic Epidemiology and Genomics, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, China, wwenhui99@163.com.
Human heredity
|April 3, 2025
概括
在类风性关节炎 (RA) 中对全基因组关联研究 (GWAS) 的本文统计分析揭示了关键的研究趋势和合作. 未来的研究前沿包括门德尔的随机化分析和RA的遗传病原体.
科学领域:
- 遗传学 遗传学 是一个
- 类风湿病学 类风湿病学
- 生物信息学是一种生物信息学.
背景情况:
- 风湿性关节炎 (RA) 构成了全球重大健康挑战,遗传因素对其发病和进展产生重大影响.
- 全基因组关联研究 (GWAS) 越来越重要,以了解RA的遗传基础.
- 这项研究涉及到日益增长的RA GWAS研究.
研究的目的:
- 进行RA GWAS出版物的全面可视化和文献计量分析.
- 确定当前的研究热点和该领域的新兴趋势.
- 促进学术合作,并预测未来的研究方向.
主要方法:
- 在文献中搜索RA和GWAS的出版物 (2002-2024) 来自Web of Science核心集合.
- 使用VOSviewer和CiteSpace进行图书统计分析,用于网络可视化.
- 审查国家,作者,机构的合作,以及出版物共同引用网络.
主要成果:
- 713 个出版物和 45,773 个引用被确定,自 2007 年以来出现了显著的激增.
- 美国在出版物方面处于领先地位;Yukinori Okada是最有影响力的作家;曼彻斯特大学是最具生产力的机构.
- 诸如"孟德尔式随机化分析"",关联"",先天性"",仪器"",偏见"",病变发生"和"全基因组关联研究"等关键词表明了研究的前沿.
结论:
- 这一分析提供了对RA GWAS研究的演变和未来轨迹的见解.
- 它强调了未来调查和潜在突破的关键领域.
- 这些发现旨在促进学术合作,并推进RA遗传学领域.
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