相关实验视频

Updated: May 22, 2025

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
10:27

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta

Published on: December 5, 2019

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全性HECT E3联酶抑制的治疗潜力

Alexander M K Rothman1, Amir Florentin2, Florence Zink3

  • 1University of Sheffield, Sheffield, UK; Novartis BioMedical Research (NBR), Cambridge, MA, USA.

Cell
|April 3, 2025
PubMed
概括

研究人员发现了全方位素E3链酶的新型抑制剂,专门针对SMURF1中的神秘腔. 这一发现通过调节BMPR2信号提供了肺动脉高血压 (PAH) 的新治疗策略.

关键词:
E6AP 其他美国一个 SMURF1整体抑制作用药物发现甘氨酸链肺动脉高血压小分子无素E3结合酶血管改造

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