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Updated: May 16, 2025

Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts
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转录向抗原映射揭示了在质母细胞瘤免疫疗法中POSTN拼接接头表位的潜力

Zujian Xiong1,2,3, Chaim T Sneiderman2, Chloe R Kuminkoski2

  • 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Genes and immunity
|April 3, 2025
PubMed
概括

瘤抗原对于质瘤免疫疗法至关重要. 研究人员确定了新的瘤丰富异型抗原 (TIA),包括POSTN-203,可以引起T细胞对质瘤细胞的反应.

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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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