心脏代谢指数作为胆结石风险的预测指标:来自NHANES 2017-2020年的证据
Huachao Zheng1, Bo Wu1, Caixiang Zhuang2
1Department of General Surgery, The Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
BMC gastroenterology
|April 4, 2025
概括
心脏代谢指数 (CMI) 与更高的胆结石风险有关. 0.85的CMI值显著预测了胆结石的患病率,特别是在女性中,有助于早期检测.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 胃肠病学 胃肠病学
背景情况:
- 心脏代谢指数 (CMI) 结合了脂质概况和腹部肥胖度的指标.
- 胆结石是一种常见的胃肠道疾病,具有重大公共卫生影响.
研究的目的:
- 调查心脏代谢指数 (CMI) 与胆结石患病率之间的关联.
- 确定CMI是否可以作为胆结石形成的预测标记.
主要方法:
- 来自NHANES 2017-2020数据集的2692名参与者的分析.
- 使用后勤回归,平滑曲线拟合和值效应分析.
- 基于自我报告数据的胆结石诊断,承认潜在的偏见.
主要成果:
- 在较高的CMI和增加胆结石风险 (OR = 1.90) 之间发现了显著的积极关联.
- 在CMI = 0.85时确定了一个值效应,低于此,胆结石风险显著增加 (OR = 2.62).
- CMI和胆结石之间的关联在女性中更为明显.
结论:
- 心脏代谢指数 (CMI) 显示了作为胆结石风险预测标记物的潜力.
- 将CMI纳入临床评估可能有助于早期发现和预防胆结石的策略.
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