老年COVID-19患者的隔膜厚度和ICU入院风险:基于CT的分析分析
Mercan Tastemur1, Cagla Ozdemir2, Esin Olcucuoğlu3
1Department of Geriatrics Medicine, Ministry of Health, Ankara City Hospital, Üniversiteler Mahallesi, Bilkent Bulvarı, No:1, Çankaya, Ankara, 06800, Turkey. dr.tastemur@gmail.com.
BMC pulmonary medicine
|April 4, 2025
概括
在老年COVID-19患者中,右膜厚度 (DT) 的增加与重症监护室 (ICU) 入院的可能性更高有关. 这一发现表明,DT可能是老年人严重COVID-19结果的有用预后标志物.
科学领域:
- 医疗成像医学成像
- 肺部病理学 肺部病理学
- 老年病的医生 老年病的医生
背景情况:
- COVID-19显著影响老年患者,往往需要密集护理.
- 隔膜功能障碍可以导致严重疾病的呼吸衰竭.
- 在老年COVID-19患者中,隔膜厚度 (DT) 的预后值仍未得到充分研究.
研究的目的:
- 调查隔膜厚度 (DT) 与COVID-19老年患者的重症监护室 (ICU) 入院需求之间的关联.
- 确定DT作为老年人群中严重的COVID-19结果的潜在预测因素.
主要方法:
- 追溯研究包括188名被诊断患有COVID-19的老年患者 (≥65岁).
- 隔膜厚度 (DT) 通过计算机断层扫描 (CT) 在右侧和左侧隔膜圆顶层测量.
- 统计分析包括后勤回归和ROC分析,以评估DT和ICU入院之间的关系.
主要成果:
- 在接受ICU治疗的患者中观察到右上角的DT.
- 多变量分析确定了右侧较高的DT,高素和IL-6水平作为ICU入院的独立预测因素.
- 接收器运行特征 (ROC) 分析表明,对于ICU需求,对正确的DT (切断值>1.8,AUC=0.632) 具有显著的预测值.
结论:
- 右侧DT升高与老年COVID-19患者ICU入院的可能性增加有关.
- DT测量,特别是右顶的测量,可以作为这个人口中的一个有价值的预后指标.
- 建议对DT测量进行进一步的研究和标准化,以便在COVID-19管理中临床应用.
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