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Updated: May 16, 2025

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
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Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets

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在PASMCs中的Piezo1:对缺氧诱导的肺高血压发展至关重要

Fenja Knoepp1, Shariq Abid2,3, Amal Houssaini2,4

  • 1Excellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus Liebig University (F.K., M.Y.G., A.G., S.K., I.B.-M., K.Q., D.F.-N., N.W.).

Circulation research
|April 4, 2025
PubMed
概括

肺动脉平滑肌细胞中的机械敏感离子通道Piezo1通过增加细胞增殖和血管收缩驱动肺高血压. 阻断Piezo1可以防止PH的发展,并保护肺血管.

关键词:
血压 血压 血压 血压细胞衰老 细胞衰老内皮细胞是内皮细胞.高血压,肺部高血压,肺部高血压.缺氧 缺氧是指缺氧的情况.血管改造 血管改造 血管改造

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