在印度预防和治疗维生素D缺乏症:一个专家小组的共识共识
Sanjay Kalra1,2, Abdul H Zargar3, Ashok K Das4
1Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
Indian journal of endocrinology and metabolism
|April 4, 2025
概括
这一共识为印度的维生素D状况提供了标准化的指导方针,解决了缺乏症并建议补充. 它旨在确保全国所有年龄组的最佳维生素D水平.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 印度维生素D缺乏的高患病率.
- 印度缺乏对维生素D状态分类,预防和治疗的标准化指南.
- 在现有指南中,维生素D缺乏和不足的截止值不一致.
研究的目的:
- 建立基于证据的共识指南,以确定印度人口中维生素D的状况.
- 解决维生素D缺乏,严重缺乏和不足的定义中的不一致性.
- 为维生素D补充策略提供明确的建议.
主要方法:
- 由印度41名内分泌学家组成的专家小组制定共识.
- 利用DELPHI方法在建议上达成高度共识.
- 定义了维生素D缺乏,严重缺乏和不足的截止值.
主要成果:
- 建立了维生素D缺乏,严重缺乏和不足的明确定义.
- 建议的目标生理25(OH) D水平为40-60 ng/mL (100-150 nmol/L).
- 为印度的不同人口群体提供了量身定制的补充剂方案.
结论:
- 该共识提供了一种统一的方法来管理印度的维生素D缺乏.
- 这些建议旨在指导医疗保健专业人员优化维生素D状态.
- 预计这些指导方针的实施将改善与维生素D相关的公共卫生结果,包括所有年龄组.
相关概念视频
Role of Skin in Vitamin D Synthesis
4.9K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
4.9K
Role of Vitamins in Maintaining Bone Health
3.1K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.1K
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.1K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.1K
Preventive Healthcare Services
954
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
954
Vitamins
514
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
514
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
259
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
259


