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表面损伤对迷你板的影响:对各种菌株的细菌附着的研究
Bramasto Purbo Sejati1, Tetiana Haniastuti2, Ahmad Kusumaatmaja3
1Departemnt of Oral and maxillofacial Surgery, Universitas Gadjah Mada, Yogyakarta, Special Region of Yogyakarta, Indonesia.
F1000Research
|April 4, 2025
概括
在面外科手术中被拒绝的小板显示表面粗度和疏水性增加,导致细菌粘附率更高. 这表明需要改进植入物表面,以防止感染和失败.
科学领域:
- 生物材料科学 生物材料科学
- 微生物学 微生物学
- 面外科手术 面外科手术
背景情况:
- 在面外科手术中,术后感染和迷你板排斥通常与表面异常和细菌粘附有关.
- 了解导致植入物失败的因素对于改善患者的治疗结果至关重要.
研究的目的:
- 调查患者拒绝的迷你板的物理和微生物特征.
- 阐明在面外科手术中导致植入物失败的因素.
主要方法:
- 使用宏观摄影和扫描电子显微镜 (SEM) 分析了40个被拒绝的微型板 (直线型BSSO和L型).
- 通过测量接触角来评估表面的湿透性.
- 使用水晶紫色测定方法量化Staphylococcus aureus,Streptococcus mutans,Pseudomonas aeruginosa和Enterococcus faecalis的细菌粘附.
主要成果:
- 与对照组相比,被拒绝的板块表现出明显的变形和显著增加的疏水性 (89.6°与72.3°相比).
- 在被拒绝的板块,特别是下板块上观察到黄金葡萄球菌和突变性菌的附着性增加.
- SEM证实了密集的细菌殖民,S. aureus和S. mutans在扭曲的表面上具有明显的聚合模式.
结论:
- 被拒绝的迷你板显示表面粗度和疏水性增加,与增强的细菌粘附相关.
- 这些发现强调了表面特性在迷你板性能中的重要性.
- 需要改进表面设计或涂层技术,以减轻生物膜的形成,并提高面外科手术的临床成功.
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