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Updated: May 16, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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同时服用埃法维伦兹和异化的药理动力学,药理遗传学和毒性

Jessica Taylor1, Gary Maartens1, Simiso Sokhela2

  • 1Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Southern African journal of HIV medicine
|April 4, 2025
PubMed
概括

服用 efavirenz 和 isoniazid 的 CYP2B6 缓慢代谢者经历了更高的药物水平和增加的 HDL 胆固醇. 这种CYP2B6基因型没有影响肝酶,葡萄糖或精神症状.

关键词:
在CYP2B6B6中.艾滋病病毒 艾滋病病毒 艾滋病病毒埃法维伦兹 (efavirenz) 是一种异化是一种异化.神经毒性的作用.

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