在耳鼻喉科临床试验中的全球作者代表性
Hong-Ho Yang1, Jeffrey D Huynh2, Clare Moffatt1
1David Geffen School of Medicine at University of California Los Angeles California USA.
Laryngoscope investigative otolaryngology
|April 4, 2025
概括
全球耳鼻喉科临床试验主要由高收入国家主导,中低收入国家增长有限,低收入国家没有代表. 这种作者差异可能会影响临床指南的全球适用性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床试验 临床试验
- 图书统计学 图书统计学
- 全球卫生平等全球卫生平等
背景情况:
- 临床试验对于推进医学知识和实践至关重要.
- 在主要医学期刊中的作者代表反映了全球研究参与.
- 了解耳鼻喉科的作者趋势对于公平的研究传播至关重要.
研究的目的:
- 分析20多年来在领先的耳鼻喉学期刊上发表的临床试验中的全球作者代表性.
- 根据作者收入水平评估试验的时间趋势和学术影响.
主要方法:
- 在四个一般耳鼻喉学期刊上对1432项临床试验 (2000-2020年) 的图书统计分析.
- 对主要作者 (第一,高级,相应) 的国籍和国家收入分类 (世界银行) 的审查.
- 多变量后勤回归用于估计时间轨迹并比较学术影响 (引用).
主要成果:
- 大多数主要作者来自非美国 (57%) 和高收入国家 (87%).
- 来自中上层 (UMIC),中下层 (LMIC) 和低收入国家 (LIC) 的试验代表性不足 (11%,3%,0%).
- LMIC的代表性略有增加 (0.26%/年),而UMIC作者主导的试验比HIC作者主导的试验引用次数更少.
结论:
- 耳鼻喉学临床试验文献在很大程度上由HIC作者主导.
- 过去二十年来,LMIC贡献的增长很小,LIC没有代表.
- 来自低收入国家的作者代表性不足可能会限制临床指南的全球适用性.
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