相关实验视频

Updated: May 16, 2025

Identification of Functional Protein Regions Through Chimeric Protein Construction
11:39

Identification of Functional Protein Regions Through Chimeric Protein Construction

Published on: January 8, 2019

10.3K

脊椎动物CPEB蛋白家族中低复杂度区域的不同演变

Serena Vaglietti1, Stefania Boggio Bozzo1, Mirella Ghirardi1

  • 1"Rita Levi-Montalcini" Department of Neuroscience, University of Turin, Turin, Italy.

Frontiers in bioinformatics
|April 4, 2025
PubMed
概括

细胞质多化元素结合蛋白 (CPEBs) 的进化在脊椎动物进化过程中显示出它们的低复杂性区域 (LCRs) 的不同趋势. 这些变化,特别是CPEB2的变化,与蛋白质功能和类年龄相关.

关键词:
CPEB 蛋白质是 CPEB 的蛋白质.细胞质多基化元素结合蛋白质.不同的进化是不同的进化.同聚合氨基酸的重复重复.液体液相分离 (LLPS) 是一种液相分离技术.低复杂度区域 (LCRs) 是一个低复杂度区域.类似的蛋白质.类蛋白质是一种类似的蛋白质.

更多相关视频

A Rapid In Vivo Bioassay for Developmentally Active Enhancers00:08

A Rapid In Vivo Bioassay for Developmentally Active Enhancers

1.2K
Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis09:38

Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis

Published on: October 16, 2016

15.8K

相关概念视频

Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
9.6K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.0K
Convergent Evolution01:54

Convergent Evolution

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
27.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.0K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.5K