胆管动力障碍症 - - 这是真的吗?
Jesse L Popover1, Zachary W Oulton1, Zachary G Brown1
1Florida Surgical Specialists, Bradenton, FL (Drs. Popover, Oulton, Brown, King, Sardzinski, Imam, Al Masri, Robles, Kannan, Gaddis, and Toomey).
胆管动力障碍是一种胆囊运动障碍,经常影响女性,并呈现出腹痛. 胆囊切除术有效地消除了这些患者的症状,即使超声检查结果正常.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
背景情况:
- 胆管动力障碍是一种功能性胆囊疾病,其特征是异常的运动性.
- 它呈现出胆道症状,但在标准成像上缺乏结构性病理.
- 诊断依赖于通过HIDA-CCK扫描的异常胆囊射出分数.
研究的目的:
- 为了研究胆囊切除术的胆道功能障碍患者的病理发现.
- 评估在此患者群体中切除胆囊后症状的消失.
主要方法:
- 从2015年至2019年对患有症状胆病或胆道功能障碍的患者进行了回顾性队列研究.
- 对临床症状,成像和外科病理学的评估.
- 主要终点:病理变化和症状消失;次要终点:与人口统计数据的相关性.
主要成果:
- 在415名患者中,89人 (21%) 患有胆道动力障碍,主要是女性 (92%),平均年龄为46岁,BMI为28岁.
- 腹部疼痛是最常见的症状 (97%).
- 病理学揭示了慢性胆囊炎在84%的胆道动力障碍患者;所有患者都经历了胆囊切除术后的症状缓解.
结论:
- 胆管动力障碍患者通常更年轻,女性,与胆病患者相比,BMI较低.
- 慢性胆囊炎的组织学证据是常见的.
- 胆囊切除术是一种有效的胆道功能障碍治疗方法,可以缓解症状,应考虑作为一线治疗.
更多相关视频
08:42Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
Published on: November 27, 2016
07:44Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
相关概念视频
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Endoscopic Procedures V: ERCP
Patient...
Depolarizing Blockers: Pharmocokinetics
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
