在接受维护血液透析的患者中,对萨尔科佩尼亚的风险预测模型:系统审查和元分析
Qing Yang1, Wenting Ji1, Julan Guo2
1College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Journal of clinical nursing
|April 4, 2025
概括
这次审查发现,虽然维持血液透析患者的肉症风险预测模型显示出良好的歧视性,但所有患者都存在偏差和不完整报告的高风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年病的医生 老年病的医生
- 生物统计学 生物统计学
背景情况:
- 在维护血液透析 (MHD) 患者中,对萨尔科佩尼亚的风险预测模型的开发正在增加.
- 这些模型的质量,适用性和报告要求对临床实用性和研究进步进行彻底评估.
研究的目的:
- 系统地审查和批判性地评估已发表的关于MHD患者肉症风险预测模型的研究.
主要方法:
- 遵循PRISMA指南的观察性研究的系统审查和元分析.
- 使用CHARMS检查清单提取数据,并使用PROBAST进行偏差风险/适用性评估.
- 使用TRIPOD声明评估报告遵守情况.
主要成果:
- 包括来自11篇文章的12个预测模型,MHD患者的肉症发病率从16.38%到37.29%不等.
- 模型显示出高度的歧视性,报告的AUC从0.73到0.955之间,联合AUC为0.91.
- 所有研究都表现出高偏差风险,主要是由于数据源问题和分析报告不佳.
结论:
- 尽管有良好的歧视,但在MHD患者中,所有审查的萨尔科佩尼亚预测模型都存在高偏差风险.
- 在所有纳入的研究中,观察到对TRIPOD报告准则的不完全遵守.
- 需要进一步的研究来提高这些模型的质量和报告,以获得可靠的临床应用.
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