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Updated: May 16, 2025

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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萨克西托克辛的宏循环:对泽特基托克辛AB的结构的洞察

Wenyuan Li1, Srinivas R Paladugu1, Jordan P Liles1

  • 1Department of Chemistry, University of Utah, Salt Lake City, UT, 84102, USA.

Chembiochem : a European journal of chemical biology
|April 4, 2025
PubMed
概括

研究人员合成了一种强大的毒素zetekitoxin AB的宏环类比物. 这些类似物显示出高活性,质疑C12水合物对于萨克西托克素类似功效的必要性.

关键词:
瓜尼迪因 (guanidine) 是一种药物.抑制剂 抑制剂 抑制剂离子通道 离子通道自然产品是自然产品的产品.毒素有毒物质 毒素有毒物质

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In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
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