使用黄类药物的抗微生物纳米技术的绿色合成:系统性审查
Cláudio Carvalho Santana Júnior1, Anamaria Mendonça Santos1, Ana Maria Santos Oliveira2
1Postgraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Journal of microencapsulation
|April 4, 2025
概括
抗菌素耐药性 (AMR) 是一个日益增长的威胁. 纳米颗粒的绿色合成使用黄胺提供了一个环保的解决方案,显示对抗性细菌的有效性,如S. aureus和E. coli.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 环境科学 环境科学
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大风险,需要新的治疗策略.
- 传统的抗生素治疗由于微生物耐药性而变得越来越无效.
- 纳米技术提供了创新的解决方案,特别是当与绿色合成等可持续实践相结合时.
研究的目的:
- 通过使用黄类药物对抗微生物纳米颗粒的绿色合成进行审查.
- 为了评估这些纳米颗粒对关键细菌病原体的疗效.
- 突出环保纳米技术在打击AMR方面的潜力.
主要方法:
- 对PubMed,Scopus,Web of Science和Embase索引的研究进行系统的文献综述.
- 确定和分析了10项关于绿色合成纳米粒子的关键研究.
- 专注于使用黄类化合物合成的纳米颗粒作为减少和稳定剂.
主要成果:
- 绿色合成有效地产生了各种金属纳米粒子 (银,金,铜).
- 这些纳米颗粒显示出对常见病原体的显著抗微生物活性,包括金黄色葡萄球菌,大肠杆菌和 Pseudomonas aeruginosa.
- 黄类化合物在纳米粒子合成中被证明是天然的减少和稳定剂.
结论:
- 绿色合成的纳米颗粒是一种有希望的,环保的方法来对抗AMR.
- 这一策略减少了对有毒化学品的依赖,并最大限度地减少了纳米粒子生产中的浪费.
- 进一步开发黄胺介导纳米颗粒可能会导致有效的新型抗菌剂.
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