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Updated: May 17, 2025

Author Spotlight: Characterizing DNA Replication of Pathogenic Repeats to Uncover Mechanisms of Replication Fork Stalling and Expansion
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对于重复诱导的点突变和重复诱导的新型过渡异色状态的核化,对于欧色重复的RID都是必要的

Zhen He1, Nannan Wu1, Ruonan Yao1

  • 1School of Life Sciences, Nanjing University, Nanjing 210023, China.

Nucleic acids research
|April 4, 2025
PubMed
概括

重复诱导的点突变 (RIP) 和异色素蛋白的形成对于基因组完整性至关重要. 这项研究表明,RID蛋白启动了这两种过程,具有独特的 euchromatic 和 heterochromatic 重复的机制.

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