结合CT结肠镜和内镜以调查结肠直肠癌的诊断收益率
A Rajendiran1, P Neupane2, V Zapadia3
1Department of General Surgery, Warrington and Halton NHS Foundation Trust, Warrington, England.
CT结肠扫描 (CTC) 显示了结肠直肠癌检测的高准确性,但错过了一些息肉. 选择性内镜可能需要改善癌症查的诊断产量.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 怀疑结肠直肠癌菌株的紧急转诊增加NHS内镜服务.
- CT结肠镜 (CTC) 提供了一个具有相似灵敏度的替代方案,但对错过的病变存在担忧.
- 结合CTC与灵活的半导体镜进行实践,但英国的指导方针质疑需要额外的内镜.
研究的目的:
- 评估是否需要在CTC旁边使用灵活的半导体镜/内镜.
- 为了减少结直肠癌诊断中不必要的内镜检查.
- 为了确定是否结合CTC和内镜可以提高诊断产量.
主要方法:
- 480名患者 (2019-2022) 的单一三级中心分析.
- 包括症状/高风险患者,监视患者和接受住院内镜检查的患者.
- 将CTC发现与内镜进行比较,将显著发现定义为≥5毫米,良性或恶性息肉.
主要成果:
- 对恶性瘤的CTC敏感度为93.3%;内镜检查为96.7%.
- 对≥5毫米的息肉的CTC敏感度为77.7%,错过了25个息肉和2种癌症.
- 大多数CTC错过的病变 (70.3%) 是左侧的.
结论:
- 在恶性瘤检测中,CTC是有效的,但在显著的多体 (≥5毫米) 中,它的敏感性比内镜要低.
- 选择性内镜评估可能是必要的,以优化诊断产量.
- 研究结果表明,CTC是一种有价值的独立工具,但内镜的作用需要仔细考虑.
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