亚当蒂诺马托斯头骨瘤石头:这是一个瘤吗?
Sérgio Cavalheiro1,2, Lorena Favaro Pavon3,4, Marcos Devanir Silva da Costa1,2
1Department of Neurology and Neurosurgery, Translational Neurosurgery Laboratory Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
概括
在阿达曼蒂诺马图斯膜瘤 (ACP) 内的结可以产生瘤,突出显示了需要彻底手术切除结的需要. 这些ACP化成分细胞为新的药物治疗和理解瘤进展提供了潜力.
科学领域:
- 在瘤学瘤学.
- 细胞生物学 细胞生物学
- 神经外科 神经外科
背景情况:
- 亚当蒂诺马图斯膜瘤 (ACP) 是细胞/细胞上区域的良性上皮瘤.
- 儿童的ACP病例往往涉及囊和化.
研究的目的:
- 为了研究非洲和非洲的化形成瘤的潜力.
- 在体外和体内建立和描述ACP化成分细胞.
- 探讨对ACP的治疗目标.
主要方法:
- 对ACP化成分进行酶性消化,以分离细胞.
- 在体外细胞培养和活力分析 (MTT试验).
- 在体内异种移植模型与MRI监测和免疫细胞化学 (cytokeratin-7).
主要成果:
- 已建立的ACP化成分细胞培养物,其翻倍时间为2天.
- 确认瘤质量来源于异种移植中的化成分细胞 (状上皮细胞).
- 在ACP化成分细胞中检测到细胞素-7的表达.
结论:
- 非洲和非洲的化物具有产生瘤的能力.
- 完整的瘤切除需要去除所有的化.
- 在研究治疗点和瘤进展机制方面,ACP化成分细胞培养有价值.
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