相关实验视频
Updated: May 17, 2025

06:22
Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
482
构建2型糖尿病与同时存在的高血压的预测模型:一个横截面研究
Huiling Zhang1,2, Shuang Yu1, Zheyuan Xia1,2
1School of Nursing, Anhui University of Traditional Chinese Medicine, Hefei, China.
Medicine
|April 4, 2025
概括
在2型糖尿病 (T2DM) 患者中早期发现高血压至关重要. 使用年龄和BMI等因素的新预测模型有助于确定高风险个体,以便及时干预.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 和高血压 (HTN) 经常同时发生,增加心血管事件,病和死亡的风险.
- 早期识别T2DM患有并发HTN高风险的患者对于个性化医疗护理和干预至关重要.
研究的目的:
- 开发和验证用于识别2型糖尿病患者高血压的预测模型.
- 帮助制定早期干预策略,并为处于危险的个人量身定制治疗计划.
主要方法:
- 一项定量观察性研究,涉及来自第三级医院的423名T2DM患者 (48.7%患有HTN).
- 用多变量逻辑回归分析来确定高血压的显著预测因素.
- 使用ROC曲线,AUC值和Hosmer-Lemeshow测试来评估模型的性能.
主要成果:
- 在T2DM患者中,高血压的重要预测因素包括年龄,酒精使用,糖尿病病,冠状动脉疾病,脑梗塞和体重指数.
- 开发的预测模型表现良好,曲线下的面积 (AUC) 为0.72.
- 霍斯默-莱梅肖测试表明,该模型很适合 (P = 0.074).
结论:
- 经过验证的预测模型有效地识别了高风险患高血压的T2DM患者.
- 这种工具可以支持早期检测,并促进个性化治疗策略,可能改善患者的治疗结果.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
Diabetes Mellitus: Overview and Type I Subtype
2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.3K
Diabetes: Symptoms, Diagnosis, and Complications
490
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
490
Carbohydrate Metabolism
10.6K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.6K
Assessment of blood pressure in brachial artery(two-step method)
633
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
633
Hypertension and Regulation of Blood Pressure
1.8K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
1.8K

