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Updated: May 17, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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MDA5ISGylation对于控制病毒复制和病变发生的免疫信号至关重要

Lucky Sarkar1, GuanQun Liu1, Dhiraj Acharya1

  • 1Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL 34987.

Proceedings of the National Academy of Sciences of the United States of America
|April 4, 2025
PubMed
概括

黑色素瘤分化相关蛋白5 (MDA5) ISGylation对于抗病毒防御至关重要. 关键位点的突变会损害MDA5信号,导致严重的病毒感染结果,突出治疗潜力.

关键词:
在ISGylation中进行化.MDA5 MDA5 MDA5 的意思是什么意思抗病毒天生的免疫力.干扰子干扰子干扰子病毒感染 病毒感染

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