在Aflibercept 8mg注射后用于湿斑退化症的闭合性视网膜血管炎
Robert A Sisk1,2,3
1Cincinnati Eye Institute, 9997 Carver Rd, Blue Ash, OH 45242, United States.
Retinal cases & brief reports
|April 4, 2025
概括
闭塞性视网膜血管炎 (ORV) 是一种罕见的并发症,用于湿性黄斑变性. 积极的类固醇治疗可以导致视力恢复,但ORV可能是慢性或复发性的.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管疾病 血管疾病
背景情况:
- 潮湿的与年龄相关的黄斑变性 (AMD) 是导致视力丧失的主要原因.
- 内抗VEGF注射是湿性AMD的标准治疗方法.
- 内注射的并发症虽然很少见,但需要谨慎管理.
研究的目的:
- 报告一个隐蔽视网膜血管炎 (ORV) 病例,该病例是在静脉内注射aflibercept 8mg后发生的.
- 描述这种罕见并发症的临床表现,诊断工作和管理.
主要方法:
- 回顾性,干预性案例报告.
- 详细审查临床表现,诊断测试和治疗过程.
- 眼科检查,实验室调查和成像研究.
主要成果:
- 一名72岁的女性在aflibercept注射后11天内产生ORV,视力从20/30到20/400丧失.
- 感染性和高凝固性工作是负面的.
- 积极的类固醇治疗 (口服,子的,静脉注射) 和流诺植入物导致视觉和解剖改善,在类固醇逐渐减少后复发.
结论:
- 闭塞性视网膜血管炎是静脉内抗VEGF治疗的罕见但严重并发症.
- 及时和积极的类固醇治疗可以导致有利的视觉结果.
- 这种情况可能是慢性或复发性的,需要长期的管理策略.
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