Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Vaccinations01:51

Vaccinations

Overview
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Community-based tuberculosis screening with computer-aided detection technology alone and in combination with point-of-care C-reactive protein testing: a paired screen-positive trial.

The Lancet. Infectious diseases·2026
Same author

A realist review to understand the complexity of effective management of type 2 diabetes and hypertension.

Public health reviews·2026
Same author

Transmission and cost-effectiveness modelling to estimate the progress towards elimination and future strategy optimisation for gambiense human African trypanosomiasis in Uganda.

BMC infectious diseases·2026
Same author

Priority implementation research for measles-rubella microarray patches identified using the Child Health and Nutrition Research Initiative methodology.

Journal of global health·2026
Same author

Economic evaluation of combination vaccines: Enabling a more comprehensive assessment of their benefits and challenges.

Vaccine·2026
Same author

Mental Health and Resilience in Eritrean and Somali Refugees in Switzerland: A Cross-Sectional Study.

International journal of public health·2026

相关实验视频

Updated: May 11, 2026

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb BCG lux/M.Tb lux
08:10

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb BCG lux/M.Tb lux

Published on: September 14, 2011

13.8K

微阵列补丁疫苗用于伤寒结合疫苗:全球性成本效益分析

Marina Antillon1, Anna Verjans1, Fayad El Sheikh2

  • 1Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland; University of Basel, Petersplatz 1, P. O. Box, 4001, Basel, Switzerland.

Vaccine
|April 4, 2025
PubMed
概括

新型伤寒联合疫苗微阵列补丁 (TCV-MAP) 可以避免数百万病例和死亡. TCV-MAP显示出成本效益,特别是在撒哈拉以南非洲,区域部署提供了显著的价值.

关键词:
经济效益性 经济效益性经济评估 经济评价微阵列贴片的贴片建模建模模型是什么台风联合疫苗 台风联合疫苗价值主张. 价值主张.

更多相关视频

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.1K
Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
06:26

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Published on: July 28, 2023

2.1K

相关实验视频

Last Updated: May 11, 2026

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb BCG lux/M.Tb lux
08:10

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb BCG lux/M.Tb lux

Published on: September 14, 2011

13.8K
Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.1K
Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
06:26

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Published on: July 28, 2023

2.1K

科学领域:

  • 全球健康 全球健康
  • 疫苗学 疫苗学 疫苗学
  • 卫生经济学 卫生经济学

背景情况:

  • 目前通过针和注射器 (TCV-N&S) 施用的伤寒联合疫苗 (TCV) 在难以接触的人群中面临覆盖范围的限制.
  • 一种新的伤寒结合疫苗呈现方式,微阵列贴片 (TCV-MAP),正在开发中,有可能改善疫苗的发放和覆盖率.

研究的目的:

  • 评估与单独使用TCV-N&S相比,TCV-MAP的成本效益.
  • 评估TCV-MAP对133个中低收入至中高收入国家的健康结果和医疗保健成本的影响.

主要方法:

  • 从20年 (2033-2052) 的医疗保健角度进行了全球扩展的成本效益分析.
  • 该分析认为TCV-MAP的成本是TCV-N&S的1.33到3倍.
  • 计算了增量成本效益比率,并与成本效益值进行了比较,并对五个国家进行了地方分析.

主要成果:

  • 与单独使用TCV-N&S相比,在全国范围内推出TCV-MAP可以避免额外的520万例病例,47,000例死亡和240万个DALY,额外成本为35亿美元.
  • 在33%的研究国家中,TCV-MAP的成本效益被证明是有效的,在撒哈拉以南非洲,这一比例达到78%.
  • 与全国推广相比,TCV-MAP的地方实施可以避免2-15%的案件,而相比全国推广的额外成本不到1-3%,从而提高价值.

结论:

  • TCV-MAP是一种潜在的成本效益策略,可以提高伤寒联合疫苗的覆盖率,特别是在资源有限的环境中.
  • TCV-MAP的价格是一个关键因素;较低的价格和战略性的区域或次国家实施提高了他们的价值主张.
  • 有针对性的TCV-MAP部署可以显著改善公共卫生结果并减少疾病负担,特别是在撒哈拉以南非洲等高发病率地区.