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归因于高BMI的全球和区域乳腺癌负担,1990-2036:全面分析

Yuzhou Cai¹, Ying Ye², Jingxian Qian³

¹Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, Yunnan, 650032, China.

|April 4, 2025

概括

高体重指数 (BMI) 在全球范围内显著推动乳腺癌,自1990年以来,死亡率和DALYs大幅增加. 肥胖管理对于制这种不断增加的健康负担至关重要,特别是在低收入地区.

科学领域:

流行病学流行病学
公共卫生公共卫生
在瘤学瘤学.

背景情况:

高体重指数 (BMI) 是包括乳腺癌在内的各种癌症的公认危险因素.
了解BMI归因于乳腺癌的流行病学趋势对于全球健康规划至关重要.

研究的目的:

从1990年到2021年,分析与高BMI相关的乳腺癌负担的全球,区域和国家趋势.
预测到2036年高BMI相关乳腺癌负担的未来趋势.

主要方法:

利用2021年全球疾病负担 (GBD) 数据集进行系统分析.
计算了204个国家和地区的年龄标准化死亡率 (ASMR) 和根据残疾调整的寿命年 (DALYs).
在未来趋势预测中采用贝叶斯年龄周期队列 (BAPC) 模型.

主要成果:

在全球范围内,高BMI归因于乳腺癌的死亡和DALY在1990年至2021年之间增加了138%以上.
虽然年龄标准化利率保持稳定,但绝对负担显著上升,特别是在社会人口指数 (SDI) 较低和中等的地区.
低SDI地区的负担增长最快,尽管高SDI地区的负担率最高.

结论:

高BMI是全球乳腺癌负担的重要和不断增长的贡献者.
这种增长趋势在收入较低的地区尤为明显,突出显示了健康结果的差异.
专注于肥胖管理的公共卫生干预措施对于减轻未来乳腺癌增加至关重要.

关键词:

乳腺癌乳腺癌乳腺癌达利斯 (DALYs) 是一种日用品.全球负担全球负担高的BMI高的BMI是一个问题.预测预测预测趋势趋势趋势

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