肌肉力量可以预测不同环境中的脆弱性和其他不良事件
Alejandro Álvarez-Bustos1, Helio J Coelho-Junior2, Jose A Carnicero3
1Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain; Instituto de Investigación IdiPaz, Madrid, Spain; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy.
下肢肌肉力量 (MP) 是老年人虚弱的关键指标. 测量MP可以帮助预测不良健康事件,并改善临床环境中的脆弱性评估.
科学领域:
- 老年学是一门学科.
- 临床生物标志物 临床生物标志物
- 老年医学 老年医学
背景情况:
- 虚弱是老年人的一个重大问题,影响健康结果.
- 下肢肌肉力量 (MP) 是身体功能和脆弱性的潜在指标.
研究的目的:
- 在老年人中使用八个尺度来评估下肢MP和虚弱之间的关联.
- 检查MP对不良健康事件的预测能力.
主要方法:
- 来自 Frailtools 项目的 245 位老年人的横截面和纵向分析.
- 通过五次坐立测试测量MP,计算绝对值,相对值和全度值.
- 使用八个尺度评估脆弱性;在12个月内追踪不良事件.
主要成果:
- 脆弱的患病率因临床环境而异,在养老院的患病率最高.
- 所有MP指标与脆弱性相关;相对MP (RMP) 显示最强的联系.
- RMP预测事件脆弱性,住院和残疾 (AUC:0.71).
结论:
- 下肢MP是老年人虚弱和不良健康事件的有效生物标志物.
- MP切线点可以提高脆弱性查,特别是在初级保健和养老院.
- 需要进一步的研究来完善特定年龄的切断值,并探索身体组成的影响.
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