在计算机断层扫描引导的在线自适应性辐射疗法中最大限度地减少肠道气体人工物,使用长时间的仰卧定位
Kendall Kiser1, Eric Laugeman1, Robbie Beckert1
1Department of Radiation Oncology, Washington University School of Medicine in St Louis.
概括
长时间躺卧可能会减少在线自适应型立体压缩放射疗法 (SABR) 治疗期间的肠道气体人工物. 验证圆束CT图像显示的文物比初始图像少,这表明肠道沉积改善了图像质量.
科学领域:
- 辐射瘤学 辐射瘤学
- 医疗成像医学成像
- 胃肠道成像学 胃肠道成像学
背景情况:
- 腹部计算机断层扫描 (CT) 引导的在线自适应式立体动态除性放射疗法 (SABR) 易受肠道气体人工物影响.
- 这种文物可能会使治疗计划和交付复杂化,可能会影响目标准确性.
研究的目的:
- 调查长时间躺卧的患者是否会减少腹部CT中的肠道气体人工物.
- 评估患者定位对在线自适应SABR的图像质量的影响.
主要方法:
- 分析了26名胰腺癌患者52个部分的1644张圆束CT (CBCT) 图像.
- 放射瘤学家,一名物理学家和一名治疗师使用1-4标签对肠道气体人工物进行了评分.
- 使用Halcyon/Ethos自适应SABR平台与HyperSight和Halcyon v3.0 CBCT成像仪获取数据.
主要成果:
- 27%的CBCT图像显示肠道气体伪造物掩盖了处于危险的器官边界.
- 与验证CBCT相比,人工物在初始CBCT中显著恶化 (平均得分为2.26对2.15,P = .006).
- 超视CBCT显示出较低的文物比例,特别是在初始扫描 (0.03对0.01).
结论:
- 与初始CBCT相比,在验证CBCT中减少了临床显著的肠道气体人工物.
- 长时间躺卧可能会促进肠道沉,从而改善在线自适应SABR的图像质量.
- 这些发现表明一种潜在的策略,以减轻腹部SABR治疗中的人工物.
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